Three-dimensional co-culture model of chronic lymphocytic leukemia bone marrow microenvironment predicts patient-specific response to mobilizing agents

Chronic lymphocytic leukemia (CLL) cells disseminate into supportive tissue microenvironments. To investigate the mechanisms involved in leukemic cell tissue retention we developed a threedimensional bone marrow (BM) microenvironment that recreates the interactions between CLL and BM stromal cells i...

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Detalles Bibliográficos
Autores principales: Barbaglio, Federica, Belloni, Daniela, Scarfò, Lydia, Sbrana, Francesca Vittoria, Ponzoni, Maurilio, Bongiovanni, Lucia, Pavesi, Luca, Zambroni, Desiree, Stamatopoulos, Kostas, Caiolfa, Valeria R., Ferrero, Elisabetta, Ghia, Paolo, Scielzo, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409046/
https://www.ncbi.nlm.nih.gov/pubmed/32732361
http://dx.doi.org/10.3324/haematol.2020.248112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409046/
https://www.ncbi.nlm.nih.gov/pubmed/32732361
http://dx.doi.org/10.3324/haematol.2020.248112

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