Inter leukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease

Sickle cell disease (SCD) is associated with chronic hemolytic anemia and a heightened inflammatory state. The causal role of inflammatory pathways in stroke associated with SCD is unclear. Therefore, the hypothesis that deletion of the non-hematopoietic interleukin-1 receptor (IL-1R) pool may be be...

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Detalles Bibliográficos
Autores principales: Venugopal, Jessica, Wang, Jintao, Mawri, Jalal, Guo, Chiao, Eitzman, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409048/
https://www.ncbi.nlm.nih.gov/pubmed/32817286
http://dx.doi.org/10.3324/haematol.2020.252395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409048/
https://www.ncbi.nlm.nih.gov/pubmed/32817286
http://dx.doi.org/10.3324/haematol.2020.252395

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