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Repurposing FDA‐Approved Compounds for the Discovery of Glutaminyl Cyclase Inhibitors as Drugs Against Alzheimer's Disease

Alzheimer's disease (AD) is one of the most common neurodegenerative causes of dementia, the pathology of which is still not much clear. It′s challenging to discover the disease modifying agents for the prevention and treatment of AD over the years. Emerging evidence has been accumulated to rev...

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Detalles Bibliográficos
Autores principales: Xu, Chenshu, Zou, Haoman, Yu, Xi, Xie, Yazhou, Cai, Jiaxin, Shang, Qi, Ouyang, Na, Wang, Yinan, Xu, Pan, He, Zhendan, Wu, Haiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409088/
https://www.ncbi.nlm.nih.gov/pubmed/33377311
http://dx.doi.org/10.1002/open.202000235