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B-Cell Compartmental Features and Molecular Basis for Therapy in Autoimmune Disease

BACKGROUND AND OBJECTIVES: To assess the molecular landscape of B-cell subpopulations across different compartments in patients with neuromyelitis optica spectrum disorder (NMOSD). METHODS: We performed B-cell transcriptomic profiles via single-cell RNA sequencing across CSF, blood, and bone marrow...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, Tian-Xiang, Liu, Ye, Jia, Dongmei, Zeng, Pei, Du, Chen, Yuan, Meng, Liu, Qiang, Wang, Yongjun, Shi, Fu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409132/
https://www.ncbi.nlm.nih.gov/pubmed/34465614
http://dx.doi.org/10.1212/NXI.0000000000001070