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Knockout of the Cannabinoid Receptor 2 Gene Promotes Inflammation and Hepatic Stellate Cell Activation by Promoting A20/Nuclear Factor-κB (NF-κB) Expression in Mice with Carbon Tetrachloride-Induced Liver Fibrosis

BACKGROUND: This study aimed to investigate the effect of deleting the cannabinoid receptor 2 (CB2) gene on the development of hepatic fibrosis induced by carbon tetrachloride (CCl(4)) in mice via regulating inflammation. MATERIAL/METHODS: The DNA was extracted from the tails of mice to identify whe...

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Detalles Bibliográficos
Autores principales: Long, Cuizhen, Xie, Na, Shu, Yuanhui, Wu, Yafeng, He, Ping, Zhou, Yan, Xiang, Yining, Gu, Junying, Yang, Lei, Wang, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409143/
https://www.ncbi.nlm.nih.gov/pubmed/34413280
http://dx.doi.org/10.12659/MSM.931236