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Cost-effective screening using a two-antibody panel for detecting mismatch repair deficiency in sporadic colorectal cancer

BACKGROUND: The microsatellite instability (MSI) test and immunohistochemistry (IHC) are widely used to screen DNA mismatch repair (MMR) deficiency in sporadic colorectal cancer (CRC). For IHC, a two-antibody panel of MLH1 and MSH2 or four-antibody panel of MLH1, MSH2, PMS2, and MSH6 are used. In ge...

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Detalles Bibliográficos
Autores principales: Kim, Jong Beom, Kim, Young Il, Yoon, Yong Sik, Kim, Jihun, Park, Seo Young, Lee, Jong Lyul, Kim, Chan Wook, Park, In Ja, Lim, Seok-Byung, Yu, Chang Sik, Kim, Jin Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409214/
https://www.ncbi.nlm.nih.gov/pubmed/34540955
http://dx.doi.org/10.12998/wjcc.v9.i24.6999