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Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model

High expression of gangliosides GD3 and GD2 is observed in human gliomas. The functions of GD3 and GD2 in malignant properties have been reported in glioma cells in vitro, but those functions have not yet been investigated in vivo. In this study, we showed that deficiency of GD3 synthase (GD3S, St8s...

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Detalles Bibliográficos
Autores principales: Ohkawa, Yuki, Zhang, Pu, Momota, Hiroyuki, Kato, Akira, Hashimoto, Noboru, Ohmi, Yuhsuke, Bhuiyan, Robiul H., Farhana, Yesmin, Natsume, Atsushi, Wakabayashi, Toshihiko, Furukawa, Keiko, Furukawa, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409297/
https://www.ncbi.nlm.nih.gov/pubmed/34145699
http://dx.doi.org/10.1111/cas.15032