Down‐regulation of Polo‐like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer

Polo‐like kinase 4 (PLK4) has been reported to contribute to tumor growth, invasion, and metastasis. However, the role of PLK4 in human bladder cancer (BC) remains unclear. Here, we demonstrate the regulatory function of PLK4 in human BC progression. PLK4 is overexpressed in BC cell lines and tissue...

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Detalles Bibliográficos
Autores principales: Yang, Ziyi, Sun, Haiyan, Ma, Wenlong, Wu, Kai, Peng, Guoyu, Ou, Tong, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409300/
https://www.ncbi.nlm.nih.gov/pubmed/34342940
http://dx.doi.org/10.1002/2211-5463.13262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409300/
https://www.ncbi.nlm.nih.gov/pubmed/34342940
http://dx.doi.org/10.1002/2211-5463.13262

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