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Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma
Temozolomide (TMZ) resistance is the main challenge in the management of glioma patients. Heparanase can mediate the secretion and function of exosomes, which are considered to be a promising molecular delivery system for cancer therapy. Therefore, this study aimed to investigate whether heparanase‐...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409313/ https://www.ncbi.nlm.nih.gov/pubmed/34036683 http://dx.doi.org/10.1111/cas.14984 |