PDL1‐positive exosomes suppress antitumor immunity by inducing tumor‐specific CD8(+) T cell exhaustion during metastasis

Metastasis is the main cause of death in individuals with cancer. Immune checkpoint blockade (ICB) can potentially reverse CD8(+) cytotoxic T lymphocytes (CTLs) dysfunction, leading to significant remission in multiple cancers. However, the mechanism underlying the development of CTL exhaustion duri...

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Detalles Bibliográficos
Autores principales: Chen, Ji, Song, Yang, Miao, Feng, Chen, Gang, Zhu, Yongjun, Wu, Ning, Pang, Liewen, Chen, Zhiming, Chen, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409314/
https://www.ncbi.nlm.nih.gov/pubmed/34152672
http://dx.doi.org/10.1111/cas.15033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409314/
https://www.ncbi.nlm.nih.gov/pubmed/34152672
http://dx.doi.org/10.1111/cas.15033

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