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PDL1‐positive exosomes suppress antitumor immunity by inducing tumor‐specific CD8(+) T cell exhaustion during metastasis

Metastasis is the main cause of death in individuals with cancer. Immune checkpoint blockade (ICB) can potentially reverse CD8(+) cytotoxic T lymphocytes (CTLs) dysfunction, leading to significant remission in multiple cancers. However, the mechanism underlying the development of CTL exhaustion duri...

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Detalles Bibliográficos
Autores principales:	Chen, Ji, Song, Yang, Miao, Feng, Chen, Gang, Zhu, Yongjun, Wu, Ning, Pang, Liewen, Chen, Zhiming, Chen, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409314/ https://www.ncbi.nlm.nih.gov/pubmed/34152672 http://dx.doi.org/10.1111/cas.15033

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