Ca(2+)‐activated K(+) channel K(Ca)1.1 as a therapeutic target to overcome chemoresistance in three‐dimensional sarcoma spheroid models

The large‐conductance Ca(2+)‐activated K(+) channel K(Ca)1.1 plays a pivotal role in tumor development and progression in several solid cancers. The three‐dimensional (3D) in vitro cell culture system is a powerful tool for cancer spheroid formation, and mimics in vivo solid tumor resistance to chem...

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Detalles Bibliográficos
Autores principales: Ohya, Susumu, Kajikuri, Junko, Endo, Kyoko, Kito, Hiroaki, Elboray, Elghareeb E., Suzuki, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409426/
https://www.ncbi.nlm.nih.gov/pubmed/34181803
http://dx.doi.org/10.1111/cas.15046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409426/
https://www.ncbi.nlm.nih.gov/pubmed/34181803
http://dx.doi.org/10.1111/cas.15046

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