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Ca(2+)‐activated K(+) channel K(Ca)1.1 as a therapeutic target to overcome chemoresistance in three‐dimensional sarcoma spheroid models
The large‐conductance Ca(2+)‐activated K(+) channel K(Ca)1.1 plays a pivotal role in tumor development and progression in several solid cancers. The three‐dimensional (3D) in vitro cell culture system is a powerful tool for cancer spheroid formation, and mimics in vivo solid tumor resistance to chem...
Autores principales: | Ohya, Susumu, Kajikuri, Junko, Endo, Kyoko, Kito, Hiroaki, Elboray, Elghareeb E., Suzuki, Takayoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409426/ https://www.ncbi.nlm.nih.gov/pubmed/34181803 http://dx.doi.org/10.1111/cas.15046 |
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