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Chromosome alignment‐maintaining phosphoprotein CHAMP1 plays a role in cell survival through regulating Mcl‐1 expression

Antimitotic drugs such as vinca alkaloids and taxanes cause mitotic cell death after prolonged mitotic arrest. However, a fraction of cells escape from mitotic arrest by undergoing mitotic slippage, which is related to resistance to antimitotic drugs. Tipping the balance to mitotic cell death thus c...

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Detalles Bibliográficos
Autores principales: Hino, Maho, Iemura, Kenji, Ikeda, Masanori, Itoh, Go, Tanaka, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409433/
https://www.ncbi.nlm.nih.gov/pubmed/34107118
http://dx.doi.org/10.1111/cas.15018