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Ruthenium(ii)-catalyzed regioselective direct C4- and C5-diamidation of indoles and mechanistic studies

A ruthenium(ii)-catalyzed regioselective direct diamidation of 3-carbonylindoles at the C4- and C5-positions using various dioxazolones is described. This novel protocol allows for the effective installation of two amide groups on the benzene ring in indole. A remarkably broad substrate scope, excel...

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Detalles Bibliográficos
Autores principales: Devkota, Shreedhar, Kim, Suyeon, Yoo, Seok Yeol, Mohandoss, Sonaimuthu, Baik, Mu-Hyun, Lee, Yong Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409494/
https://www.ncbi.nlm.nih.gov/pubmed/34567497
http://dx.doi.org/10.1039/d1sc02138a