IGFBP‐3 and TGF‐β inhibit growth in epithelial cells by stimulating type V TGF‐β receptor (TβR‐V)‐mediated tumor suppressor signaling

The TGF‐β type V receptor (TβR‐V) mediates growth inhibition by IGFBP‐3 and TGF‐β in epithelial cells and loss of TβR‐V expression in these cells leads to development of carcinoma. The mechanisms by which TβR‐V mediates growth inhibition (tumor suppressor) signaling remain elusive. Previous studies...

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Detalles Bibliográficos
Autores principales: Chen, Chun‐Lin, Huang, Franklin W., Huang, Shuan Shian, Huang, Jung San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409558/
https://www.ncbi.nlm.nih.gov/pubmed/34485840
http://dx.doi.org/10.1096/fba.2021-00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409558/
https://www.ncbi.nlm.nih.gov/pubmed/34485840
http://dx.doi.org/10.1096/fba.2021-00016

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