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Imprecise recombinant viruses evolve via a fitness-driven, iterative process of polymerase template-switching events

Recombination is a common feature of many positive-strand RNA viruses, playing an important role in virus evolution. However, to date, there is limited understanding of the mechanisms behind the process. Utilising in vitro assays, we have previously shown that the template-switching event of recombi...

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Detalles Bibliográficos
Autores principales: Bentley, Kirsten, Alnaji, Fadi Ghassan, Woodford, Luke, Jones, Siân, Woodman, Andrew, Evans, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409635/
https://www.ncbi.nlm.nih.gov/pubmed/34415977
http://dx.doi.org/10.1371/journal.ppat.1009676