Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort

BACKGROUND: Thoracic aortic aneurysm (TAA) and abdominal aortic aneurysm (AAA) are known to have a strong genetic component. METHODS AND RESULTS: In a genome-wide association study (GWAS) using the UK Biobank, we analyzed the genomes of 1,363 individuals with AAA compared to 27,260 age, ancestry, an...

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Detalles Bibliográficos
Autores principales: Ashvetiya, Tamara, Fan, Sherry X., Chen, Yi-Ju, Williams, Charles H., O’Connell, Jeffery R., Perry, James A., Hong, Charles C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409653/
https://www.ncbi.nlm.nih.gov/pubmed/34469433
http://dx.doi.org/10.1371/journal.pone.0247287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409653/
https://www.ncbi.nlm.nih.gov/pubmed/34469433
http://dx.doi.org/10.1371/journal.pone.0247287

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