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Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort
BACKGROUND: Thoracic aortic aneurysm (TAA) and abdominal aortic aneurysm (AAA) are known to have a strong genetic component. METHODS AND RESULTS: In a genome-wide association study (GWAS) using the UK Biobank, we analyzed the genomes of 1,363 individuals with AAA compared to 27,260 age, ancestry, an...
Autores principales: | Ashvetiya, Tamara, Fan, Sherry X., Chen, Yi-Ju, Williams, Charles H., O’Connell, Jeffery R., Perry, James A., Hong, Charles C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409653/ https://www.ncbi.nlm.nih.gov/pubmed/34469433 http://dx.doi.org/10.1371/journal.pone.0247287 |
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