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High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes

PURPOSE: Obesity is a major public health problem. Understanding which genes contribute to obesity may better predict individual risk and allow development of new therapies. Because obesity of a mouse gene knockout (KO) line predicts an association of the orthologous human gene with obesity, we revi...

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Detalles Bibliográficos
Autores principales: Powell, David R, Revelli, Jean-Pierre, Doree, Deon D, DaCosta, Christopher M, Desai, Urvi, Shadoan, Melanie K, Rodriguez, Lawrence, Mullens, Michael, Yang, Qi M, Ding, Zhi-Ming, Kirkpatrick, Laura L, Vogel, Peter, Zambrowicz, Brian, Sands, Arthur T, Platt, Kenneth A, Hansen, Gwenn M, Brommage, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409770/
https://www.ncbi.nlm.nih.gov/pubmed/34483672
http://dx.doi.org/10.2147/DMSO.S322083