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Glyoxal‐induced formation of advanced glycation end‐products in type 1 collagen decreases both its strength and flexibility in vitro

The high plasma glucose induced in glucose metabolism disorders leads to the non‐enzymatic glucose‐dependent modification (glycation) of type 1 collagen, which is an essential component of bone tissue. The glycation of proteins induces the formation of advanced glycation end‐products, such as carbox...

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Detalles Bibliográficos
Autores principales: Kitamura, Kei‐ichiro, Hirayama, Jun, Tabuchi, Yoshiaki, Minami, Takao, Matsubara, Hajime, Hattori, Atsuhiko, Suzuki, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409810/
https://www.ncbi.nlm.nih.gov/pubmed/33605082
http://dx.doi.org/10.1111/jdi.13528