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Serum selenium levels and asthma among seafood processing workers in Greenland

Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers,...

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Autores principales: Laustsen, Birgitte Hamann, Omland, Øyvind, Würtz, Else Toft, Jørgensen, Louise, Bønløkke, Jakob Hjort
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409947/
https://www.ncbi.nlm.nih.gov/pubmed/34455939
http://dx.doi.org/10.1080/22423982.2021.1972525
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author Laustsen, Birgitte Hamann
Omland, Øyvind
Würtz, Else Toft
Jørgensen, Louise
Bønløkke, Jakob Hjort
author_facet Laustsen, Birgitte Hamann
Omland, Øyvind
Würtz, Else Toft
Jørgensen, Louise
Bønløkke, Jakob Hjort
author_sort Laustsen, Birgitte Hamann
collection PubMed
description Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers, to compare with levels recorded in previous decades and to establish if s-Se is associated with asthma or lung function. Data, including questionnaire answers, spirometry, skin-prick test and s-Se from 324 seafood processing workers in Greenland were collected during 2016–2017. Mean s-Se values were compared by t-test and one-way ANOVA. Associations between s-Se and asthma, symptoms from the lower airways at work and lung function were assessed using linear regression. The mean s-Se was 96.2 µg/L. S-Se was higher among non-smokers and workers living in settlements. Workers with asthma did not have s-Se levels significantly different from those of non-asthmatics. We found a positive association between s-Se levels and FEV(1) values. Selenium levels appear to continue declining in Greenland, presumably because of a more Westernised lifestyle. The health effects of declining Selenium levels remain unclear. We did not establish an association between s-Se and asthma, but we did record a positive association between s-Se and FEV(1).
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spelling pubmed-84099472021-09-02 Serum selenium levels and asthma among seafood processing workers in Greenland Laustsen, Birgitte Hamann Omland, Øyvind Würtz, Else Toft Jørgensen, Louise Bønløkke, Jakob Hjort Int J Circumpolar Health Original Research Article Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers, to compare with levels recorded in previous decades and to establish if s-Se is associated with asthma or lung function. Data, including questionnaire answers, spirometry, skin-prick test and s-Se from 324 seafood processing workers in Greenland were collected during 2016–2017. Mean s-Se values were compared by t-test and one-way ANOVA. Associations between s-Se and asthma, symptoms from the lower airways at work and lung function were assessed using linear regression. The mean s-Se was 96.2 µg/L. S-Se was higher among non-smokers and workers living in settlements. Workers with asthma did not have s-Se levels significantly different from those of non-asthmatics. We found a positive association between s-Se levels and FEV(1) values. Selenium levels appear to continue declining in Greenland, presumably because of a more Westernised lifestyle. The health effects of declining Selenium levels remain unclear. We did not establish an association between s-Se and asthma, but we did record a positive association between s-Se and FEV(1). Taylor & Francis 2021-08-28 /pmc/articles/PMC8409947/ /pubmed/34455939 http://dx.doi.org/10.1080/22423982.2021.1972525 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Article
Laustsen, Birgitte Hamann
Omland, Øyvind
Würtz, Else Toft
Jørgensen, Louise
Bønløkke, Jakob Hjort
Serum selenium levels and asthma among seafood processing workers in Greenland
title Serum selenium levels and asthma among seafood processing workers in Greenland
title_full Serum selenium levels and asthma among seafood processing workers in Greenland
title_fullStr Serum selenium levels and asthma among seafood processing workers in Greenland
title_full_unstemmed Serum selenium levels and asthma among seafood processing workers in Greenland
title_short Serum selenium levels and asthma among seafood processing workers in Greenland
title_sort serum selenium levels and asthma among seafood processing workers in greenland
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409947/
https://www.ncbi.nlm.nih.gov/pubmed/34455939
http://dx.doi.org/10.1080/22423982.2021.1972525
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