Cargando…
Serum selenium levels and asthma among seafood processing workers in Greenland
Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers,...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409947/ https://www.ncbi.nlm.nih.gov/pubmed/34455939 http://dx.doi.org/10.1080/22423982.2021.1972525 |
_version_ | 1783747065152536576 |
---|---|
author | Laustsen, Birgitte Hamann Omland, Øyvind Würtz, Else Toft Jørgensen, Louise Bønløkke, Jakob Hjort |
author_facet | Laustsen, Birgitte Hamann Omland, Øyvind Würtz, Else Toft Jørgensen, Louise Bønløkke, Jakob Hjort |
author_sort | Laustsen, Birgitte Hamann |
collection | PubMed |
description | Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers, to compare with levels recorded in previous decades and to establish if s-Se is associated with asthma or lung function. Data, including questionnaire answers, spirometry, skin-prick test and s-Se from 324 seafood processing workers in Greenland were collected during 2016–2017. Mean s-Se values were compared by t-test and one-way ANOVA. Associations between s-Se and asthma, symptoms from the lower airways at work and lung function were assessed using linear regression. The mean s-Se was 96.2 µg/L. S-Se was higher among non-smokers and workers living in settlements. Workers with asthma did not have s-Se levels significantly different from those of non-asthmatics. We found a positive association between s-Se levels and FEV(1) values. Selenium levels appear to continue declining in Greenland, presumably because of a more Westernised lifestyle. The health effects of declining Selenium levels remain unclear. We did not establish an association between s-Se and asthma, but we did record a positive association between s-Se and FEV(1). |
format | Online Article Text |
id | pubmed-8409947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-84099472021-09-02 Serum selenium levels and asthma among seafood processing workers in Greenland Laustsen, Birgitte Hamann Omland, Øyvind Würtz, Else Toft Jørgensen, Louise Bønløkke, Jakob Hjort Int J Circumpolar Health Original Research Article Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers, to compare with levels recorded in previous decades and to establish if s-Se is associated with asthma or lung function. Data, including questionnaire answers, spirometry, skin-prick test and s-Se from 324 seafood processing workers in Greenland were collected during 2016–2017. Mean s-Se values were compared by t-test and one-way ANOVA. Associations between s-Se and asthma, symptoms from the lower airways at work and lung function were assessed using linear regression. The mean s-Se was 96.2 µg/L. S-Se was higher among non-smokers and workers living in settlements. Workers with asthma did not have s-Se levels significantly different from those of non-asthmatics. We found a positive association between s-Se levels and FEV(1) values. Selenium levels appear to continue declining in Greenland, presumably because of a more Westernised lifestyle. The health effects of declining Selenium levels remain unclear. We did not establish an association between s-Se and asthma, but we did record a positive association between s-Se and FEV(1). Taylor & Francis 2021-08-28 /pmc/articles/PMC8409947/ /pubmed/34455939 http://dx.doi.org/10.1080/22423982.2021.1972525 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Article Laustsen, Birgitte Hamann Omland, Øyvind Würtz, Else Toft Jørgensen, Louise Bønløkke, Jakob Hjort Serum selenium levels and asthma among seafood processing workers in Greenland |
title | Serum selenium levels and asthma among seafood processing workers in Greenland |
title_full | Serum selenium levels and asthma among seafood processing workers in Greenland |
title_fullStr | Serum selenium levels and asthma among seafood processing workers in Greenland |
title_full_unstemmed | Serum selenium levels and asthma among seafood processing workers in Greenland |
title_short | Serum selenium levels and asthma among seafood processing workers in Greenland |
title_sort | serum selenium levels and asthma among seafood processing workers in greenland |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409947/ https://www.ncbi.nlm.nih.gov/pubmed/34455939 http://dx.doi.org/10.1080/22423982.2021.1972525 |
work_keys_str_mv | AT laustsenbirgittehamann serumseleniumlevelsandasthmaamongseafoodprocessingworkersingreenland AT omlandøyvind serumseleniumlevelsandasthmaamongseafoodprocessingworkersingreenland AT wurtzelsetoft serumseleniumlevelsandasthmaamongseafoodprocessingworkersingreenland AT jørgensenlouise serumseleniumlevelsandasthmaamongseafoodprocessingworkersingreenland AT bønløkkejakobhjort serumseleniumlevelsandasthmaamongseafoodprocessingworkersingreenland |