In vitro and in silico studies of bis (indol-3-yl) methane derivatives as potential α-glucosidase and α-amylase inhibitors

In this paper, bis (indol-3-yl) methanes (BIMs) were synthesised and evaluated for their inhibitory activity against α-glucosidase and α-amylase. All synthesised compounds showed potential α-glucosidase and α-amylase inhibitory activities. Compounds 5 g (IC(50): 7.54 ± 1.10 μM), 5e (IC(50): 9.00 ± 0...

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Detalles Bibliográficos
Autores principales: Zheng, Peng-Fei, Xiong, Zhuang, Liao, Cui-ying, Zhang, Xin, Feng, Mei, Wu, Xiao-Zheng, Lin, Jing, Lei, Lin-Sheng, Zhang, You-Cheng, Wang, Shao-Hua, Xu, Xue-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409970/
https://www.ncbi.nlm.nih.gov/pubmed/34459690
http://dx.doi.org/10.1080/14756366.2021.1971976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409970/
https://www.ncbi.nlm.nih.gov/pubmed/34459690
http://dx.doi.org/10.1080/14756366.2021.1971976

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