Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles

A series of 6-amidinobenzothiazoles, linked via phenoxymethylene or directly to the 1,2,3-triazole ring with a p-substituted phenyl or benzyl moiety, were synthesised and evaluated in vitro against four human tumour cell lines and the protozoan parasite Trypanosoma brucei. The influence of the type...

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Detalles Bibliográficos
Autores principales: Racané, Livio, Rep, Valentina, Kraljević Pavelić, Sandra, Grbčić, Petra, Zonjić, Iva, Radić Stojković, Marijana, Taylor, Martin C., Kelly, John M., Raić-Malić, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409973/
https://www.ncbi.nlm.nih.gov/pubmed/34455887
http://dx.doi.org/10.1080/14756366.2021.1959572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409973/
https://www.ncbi.nlm.nih.gov/pubmed/34455887
http://dx.doi.org/10.1080/14756366.2021.1959572

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