Cargando…

Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication

Historically, naive cells have been considered inconsequential to HIV persistence. Here, we compared the contributions of naive and memory cells to the reservoirs of individuals with a spectrum of reservoir sizes and variable immunological control. We performed proviral sequencing of approximately 6...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinzone, Marilia R., Weissman, Sam, Pasternak, Alexander O., Zurakowski, Ryan, Migueles, Stephen, O’Doherty, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409977/
https://www.ncbi.nlm.nih.gov/pubmed/34228640
http://dx.doi.org/10.1172/jci.insight.150794