HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

SARS-CoV-2 infects epithelial cells of the human gastrointestinal (GI) tract and causes related symptoms. HIV infection impairs gut homeostasis and is associated with an increased risk of COVID-19 fatality. To investigate the potential link between these observations, we analyzed single-cell transcr...

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Detalles Bibliográficos
Autores principales: Fardoos, Rabiah, Asowata, Osaretin E., Herbert, Nicholas, Nyquist, Sarah K., Zungu, Yenzekile, Singh, Alveera, Ngoepe, Abigail, Mbano, Ian M., Mthabela, Ntombifuthi, Ramjit, Dirhona, Karim, Farina, Kuhn, Warren, Madela, Fusi G., Manzini, Vukani T., Anderson, Frank, Berger, Bonnie, Pers, Tune H., Shalek, Alex K., Leslie, Alasdair, Kløverpris, Henrik N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Resource and Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409978/
https://www.ncbi.nlm.nih.gov/pubmed/34252054
http://dx.doi.org/10.1172/jci.insight.148920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409978/
https://www.ncbi.nlm.nih.gov/pubmed/34252054
http://dx.doi.org/10.1172/jci.insight.148920

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