Cell differentiation is disrupted by MYO5B loss through Wnt/Notch imbalance

Functional loss of myosin Vb (MYO5B) induces a variety of deficits in intestinal epithelial cell function and causes a congenital diarrheal disorder, microvillus inclusion disease (MVID). The impact of MYO5B loss on differentiated cell lineage choice has not been investigated. We quantified the popu...

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Detalles Bibliográficos
Autores principales: Kaji, Izumi, Roland, Joseph T., Rathan-Kumar, Sudiksha, Engevik, Amy C., Burman, Andreanna, Goldstein, Anna E., Watanabe, Masahiko, Goldenring, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409988/
https://www.ncbi.nlm.nih.gov/pubmed/34197342
http://dx.doi.org/10.1172/jci.insight.150416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409988/
https://www.ncbi.nlm.nih.gov/pubmed/34197342
http://dx.doi.org/10.1172/jci.insight.150416

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