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PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+γδ Treg polarization
The γδ T cell is a promising candidate cell in tumor immunotherapy. However, γδ T cells polarize to CD39(+)γδ Tregs upon colorectal cancer (CRC) induction, and the underlying mechanism remains unclear. Here, we show that the frequency of CD39(+)γδ Tregs, which positively correlated with poor prognos...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409991/ https://www.ncbi.nlm.nih.gov/pubmed/34283812 http://dx.doi.org/10.1172/jci.insight.148028 |