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The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease

Alcohol-associated liver disease (ALD) represents a spectrum of histopathological changes, including alcoholic steatosis, steatohepatitis, and cirrhosis. One of the early responses to excessive alcohol consumption is lipid accumulation in the hepatocytes. Lipid ω-hydroxylation of medium- and long-ch...

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Detalles Bibliográficos
Autores principales: Yang, Zhihong, Smalling, Rana V., Huang, Yi, Jiang, Yanchao, Kusumanchi, Praveen, Bogaert, Will, Wang, Li, Delker, Don A., Skill, Nicholas J., Han, Sen, Zhang, Ting, Ma, Jing, Huda, Nazmul, Liangpunsakul, Suthat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410014/
https://www.ncbi.nlm.nih.gov/pubmed/34423788
http://dx.doi.org/10.1172/jci.insight.140687