Cargando…

Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantation

TCR repertoire diversification constitutes a foundation for successful immune reconstitution after allogeneic hematopoietic cell transplantation (allo-HCT). Deep TCR Vβ sequencing of 135 serial specimens from a cohort of 35 allo-HCT recipients/donors was performed to dissect posttransplant TCR archi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pagliuca, Simona, Gurnari, Carmelo, Hong, Sanghee, Zhao, Ran, Kongkiatkamon, Sunisa, Terkawi, Laila, Zawit, Misam, Guan, Yihong, Awada, Hassan, Kishtagari, Ashwin, Kerr, Cassandra M., LaFramboise, Thomas, Patel, Bhumika J., Jha, Babal K., Carraway, Hetty E., Visconte, Valeria, Majhail, Navneet S., Hamilton, Betty K., Maciejewski, Jaroslaw P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410023/
https://www.ncbi.nlm.nih.gov/pubmed/34236054
http://dx.doi.org/10.1172/jci.insight.149080