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Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantation
TCR repertoire diversification constitutes a foundation for successful immune reconstitution after allogeneic hematopoietic cell transplantation (allo-HCT). Deep TCR Vβ sequencing of 135 serial specimens from a cohort of 35 allo-HCT recipients/donors was performed to dissect posttransplant TCR archi...
Autores principales: | Pagliuca, Simona, Gurnari, Carmelo, Hong, Sanghee, Zhao, Ran, Kongkiatkamon, Sunisa, Terkawi, Laila, Zawit, Misam, Guan, Yihong, Awada, Hassan, Kishtagari, Ashwin, Kerr, Cassandra M., LaFramboise, Thomas, Patel, Bhumika J., Jha, Babal K., Carraway, Hetty E., Visconte, Valeria, Majhail, Navneet S., Hamilton, Betty K., Maciejewski, Jaroslaw P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410023/ https://www.ncbi.nlm.nih.gov/pubmed/34236054 http://dx.doi.org/10.1172/jci.insight.149080 |
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