Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals

Recent advances in high-throughput T cell receptor (TCR) sequencing have allowed for new insights into the human TCR repertoire. However, methods for capturing antigen-specific repertoires remain an area of development. Here, we describe a potentially novel approach that utilizes both a biological a...

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Detalles Bibliográficos
Autores principales: Smith, Neal P., Ruiter, Bert, Virkud, Yamini V., Tu, Ang A., Monian, Brinda, Moon, James J., Love, J. Christopher, Shreffler, Wayne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Resource and Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410028/
https://www.ncbi.nlm.nih.gov/pubmed/34032640
http://dx.doi.org/10.1172/jci.insight.140028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410028/
https://www.ncbi.nlm.nih.gov/pubmed/34032640
http://dx.doi.org/10.1172/jci.insight.140028

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