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Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals
Recent advances in high-throughput T cell receptor (TCR) sequencing have allowed for new insights into the human TCR repertoire. However, methods for capturing antigen-specific repertoires remain an area of development. Here, we describe a potentially novel approach that utilizes both a biological a...
Autores principales: | Smith, Neal P., Ruiter, Bert, Virkud, Yamini V., Tu, Ang A., Monian, Brinda, Moon, James J., Love, J. Christopher, Shreffler, Wayne G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410028/ https://www.ncbi.nlm.nih.gov/pubmed/34032640 http://dx.doi.org/10.1172/jci.insight.140028 |
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