Early defects in mucopolysaccharidosis type IIIC disrupt excitatory synaptic transmission

The majority of patients affected with lysosomal storage disorders (LSD) exhibit neurological symptoms. For mucopolysaccharidosis type IIIC (MPSIIIC), the major burdens are progressive and severe neuropsychiatric problems and dementia, primarily thought to stem from neurodegeneration. Using the MPSI...

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Detalles Bibliográficos
Autores principales: Pará, Camila, Bose, Poulomee, Bruno, Luigi, Freemantle, Erika, Taherzadeh, Mahsa, Pan, Xuefang, Han, Chanshuai, McPherson, Peter S., Lacaille, Jean-Claude, Bonneil, Éric, Thibault, Pierre, O’Leary, Claire, Bigger, Brian, Morales, Carlos Ramon, Di Cristo, Graziella, Pshezhetsky, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410035/
https://www.ncbi.nlm.nih.gov/pubmed/34156977
http://dx.doi.org/10.1172/jci.insight.142073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410035/
https://www.ncbi.nlm.nih.gov/pubmed/34156977
http://dx.doi.org/10.1172/jci.insight.142073

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