Inflammatory signals are sufficient to elicit TOX expression in mouse and human CD8(+) T cells

T cell receptor (TCR) stimulation leads to the expression of the transcription factor thymocyte selection–associated high-mobility group box (TOX). Prolonged TCR signaling, such as encountered during chronic infections or in tumors, leads to sustained TOX expression, which is required for the induct...

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Detalles Bibliográficos
Autores principales: Maurice, Nicholas J., Berner, Jacqueline, Taber, Alexis K., Zehn, Dietmar, Prlic, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410038/
https://www.ncbi.nlm.nih.gov/pubmed/34032638
http://dx.doi.org/10.1172/jci.insight.150744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410038/
https://www.ncbi.nlm.nih.gov/pubmed/34032638
http://dx.doi.org/10.1172/jci.insight.150744

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