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Endothelial STING controls T cell transmigration in an IFNI-dependent manner

The stimulator of IFN genes (STING) protein senses cyclic dinucleotides released in response to double-stranded DNA and functions as an adaptor molecule for type I IFN (IFNI) signaling by activating IFNI-stimulated genes (ISG). We found impaired T cell infiltration into the peritoneum in response to...

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Detalles Bibliográficos
Autores principales: Anastasiou, Marina, Newton, Gail A., Kaur, Kuljeet, Carrillo-Salinas, Francisco J., Smolgovsky, Sasha A., Bayer, Abraham L., Ilyukha, Vladimir, Sharma, Shruti, Poltorak, Alexander, Luscinskas, Francis W., Alcaide, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410041/
https://www.ncbi.nlm.nih.gov/pubmed/34156982
http://dx.doi.org/10.1172/jci.insight.149346