Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA

Taspase1, a highly conserved threonine protease encoded by TASP1, cleaves nuclear histone-modifying factors and basal transcription regulators to orchestrate diverse transcription programs. Hereditary loss-of-function mutation of TASP1 has recently been reported in humans as resulting in an anomaly...

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Detalles Bibliográficos
Autores principales: Niizuma, Hidetaka, Searleman, Adam C., Takeda, Shugaku, Armstrong, Scott A., Park, Christopher Y., Cheng, Emily H., Hsieh, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410044/
https://www.ncbi.nlm.nih.gov/pubmed/34156981
http://dx.doi.org/10.1172/jci.insight.149382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410044/
https://www.ncbi.nlm.nih.gov/pubmed/34156981
http://dx.doi.org/10.1172/jci.insight.149382

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