KRAS-driven model of Gorham-Stout disease effectively treated with trametinib

Gorham-Stout disease (GSD) is a sporadically occurring lymphatic disorder. Patients with GSD develop ectopic lymphatics in bone, gradually lose bone, and can have life-threatening complications, such as chylothorax. The etiology of GSD is poorly understood, and current treatments for this disease ar...

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Detalles Bibliográficos
Autores principales: Homayun-Sepehr, Nassim, McCarter, Anna L., Helaers, Raphaël, Galant, Christine, Boon, Laurence M., Brouillard, Pascal, Vikkula, Miikka, Dellinger, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410066/
https://www.ncbi.nlm.nih.gov/pubmed/34156985
http://dx.doi.org/10.1172/jci.insight.149831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410066/
https://www.ncbi.nlm.nih.gov/pubmed/34156985
http://dx.doi.org/10.1172/jci.insight.149831

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