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Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity

Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and for promoting resolution, and they are protective in preclinical sepsis models. Here, in human sepsis, we mapped reso...

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Detalles Bibliográficos
Autores principales: Jundi, Bakr, Lee, Do-Hyun, Jeon, Hyungkook, Duvall, Melody G., Nijmeh, Julie, Abdulnour, Raja-Elie E., Pinilla-Vera, Mayra, Baron, Rebecca M., Han, Jongyoon, Voldman, Joel, Levy, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410067/
https://www.ncbi.nlm.nih.gov/pubmed/34166226
http://dx.doi.org/10.1172/jci.insight.148866