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Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity
Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and for promoting resolution, and they are protective in preclinical sepsis models. Here, in human sepsis, we mapped reso...
Autores principales: | Jundi, Bakr, Lee, Do-Hyun, Jeon, Hyungkook, Duvall, Melody G., Nijmeh, Julie, Abdulnour, Raja-Elie E., Pinilla-Vera, Mayra, Baron, Rebecca M., Han, Jongyoon, Voldman, Joel, Levy, Bruce D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410067/ https://www.ncbi.nlm.nih.gov/pubmed/34166226 http://dx.doi.org/10.1172/jci.insight.148866 |
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