TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

The signalling pathways that maintain primed human pluripotent stem cells (hPSCs) have been well characterised, revealing a critical role for TGFβ/Activin/Nodal signalling. In contrast, the signalling requirements of naïve human pluripotency have not been fully established. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Osnato, Anna, Brown, Stephanie, Krueger, Christel, Andrews, Simon, Collier, Amanda J, Nakanoh, Shota, Quiroga Londoño, Mariana, Wesley, Brandon T, Muraro, Daniele, Brumm, A Sophie, Niakan, Kathy K, Vallier, Ludovic, Ortmann, Daniel, Rugg-Gunn, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410071/
https://www.ncbi.nlm.nih.gov/pubmed/34463252
http://dx.doi.org/10.7554/eLife.67259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410071/
https://www.ncbi.nlm.nih.gov/pubmed/34463252
http://dx.doi.org/10.7554/eLife.67259

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