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MCL1 participates in leptin-promoted mitochondrial fusion and contributes to drug resistance in gallbladder cancer
Obesity is a risk factor for gallbladder cancer (GBC) development, and it correlates with shorter overall survival. Leptin, derived from adipocytes, has been suggested to contribute to the growth of cancer cells; however, the detailed mechanism of leptin in GBC drug resistance remains uninvestigated...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410075/ https://www.ncbi.nlm.nih.gov/pubmed/34156978 http://dx.doi.org/10.1172/jci.insight.135438 |