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Glypicans define unique roles for the Hedgehog co-receptors boi and ihog in cytoneme-mediated gradient formation

The conserved family of Hedgehog (Hh) signaling proteins plays a key role in cell–cell communication in development, tissue repair, and cancer progression, inducing distinct concentration-dependent responses in target cells located at short and long distances. One simple mechanism for long distance...

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Detalles Bibliográficos
Autores principales: Simon, Eléanor, Jiménez-Jiménez, Carlos, Seijo-Barandiarán, Irene, Aguilar, Gustavo, Sánchez-Hernández, David, Aguirre-Tamaral, Adrián, González-Méndez, Laura, Ripoll, Pedro, Guerrero, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410076/
https://www.ncbi.nlm.nih.gov/pubmed/34355694
http://dx.doi.org/10.7554/eLife.64581