The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging

Mitochondrial activity determines aging rate and the onset of chronic diseases. The mitochondrial permeability transition pore (mPTP) is a pathological pore in the inner mitochondrial membrane thought to be composed of the F-ATP synthase (complex V). OSCP, a subunit of F-ATP synthase, helps protect...

Descripción completa

Detalles Bibliográficos
Autores principales: Angeli, Suzanne, Foulger, Anna, Chamoli, Manish, Peiris, Tanuja Harshani, Gerencser, Akos, Shahmirzadi, Azar Asadi, Andersen, Julie, Lithgow, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410078/
https://www.ncbi.nlm.nih.gov/pubmed/34467850
http://dx.doi.org/10.7554/eLife.63453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410078/
https://www.ncbi.nlm.nih.gov/pubmed/34467850
http://dx.doi.org/10.7554/eLife.63453

Ejemplares similares