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Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions

Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs, and LDLs and is essential for their production. Defects in ApoB synthesis and secretion result in several human diseases, including abetalipoproteinemia and familial hypobetalipoproteinemia (FHBL1). In addition, ApoB-related dysl...

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Detalles Bibliográficos
Autores principales: Templehof, Hanoch, Moshe, Noga, Avraham-Davidi, Inbal, Yaniv, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410079/
https://www.ncbi.nlm.nih.gov/pubmed/34236046
http://dx.doi.org/10.1172/jci.insight.130399