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Plasma 1,3-β-d-glucan levels predict adverse clinical outcomes in critical illness

BACKGROUND: The fungal cell wall constituent 1,3-β-d-glucan (BDG) is a pathogen-associated molecular pattern that can stimulate innate immunity. We hypothesized that BDG from colonizing fungi in critically ill patients may translocate into the systemic circulation and be associated with host inflamm...

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Detalles Bibliográficos
Autores principales: Kitsios, Georgios D., Kotok, Daniel, Yang, Haopu, Finkelman, Malcolm A., Zhang, Yonglong, Britton, Noel, Li, Xiaoyun, Levochkina, Marina S., Wagner, Amy K., Schaefer, Caitlin, Villandre, John J., Guo, Rui, Evankovich, John W., Bain, William, Shah, Faraaz, Zhang, Yingze, Methé, Barbara A., Benos, Panayiotis V., McVerry, Bryan J., Morris, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410081/
https://www.ncbi.nlm.nih.gov/pubmed/34128840
http://dx.doi.org/10.1172/jci.insight.141277