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Plasma 1,3-β-d-glucan levels predict adverse clinical outcomes in critical illness
BACKGROUND: The fungal cell wall constituent 1,3-β-d-glucan (BDG) is a pathogen-associated molecular pattern that can stimulate innate immunity. We hypothesized that BDG from colonizing fungi in critically ill patients may translocate into the systemic circulation and be associated with host inflamm...
Autores principales: | Kitsios, Georgios D., Kotok, Daniel, Yang, Haopu, Finkelman, Malcolm A., Zhang, Yonglong, Britton, Noel, Li, Xiaoyun, Levochkina, Marina S., Wagner, Amy K., Schaefer, Caitlin, Villandre, John J., Guo, Rui, Evankovich, John W., Bain, William, Shah, Faraaz, Zhang, Yingze, Methé, Barbara A., Benos, Panayiotis V., McVerry, Bryan J., Morris, Alison |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410081/ https://www.ncbi.nlm.nih.gov/pubmed/34128840 http://dx.doi.org/10.1172/jci.insight.141277 |
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