Type II alveolar epithelial cell–specific loss of RhoA exacerbates allergic airway inflammation through SLC26A4

The small GTPase RhoA and its downstream effectors are critical regulators in the pathophysiological processes of asthma. The underlying mechanism, however, remains undetermined. Here, we generated an asthma mouse model with RhoA–conditional KO mice (Sftpc-cre;RhoA(fl/fl)) in type II alveolar epithe...

Descripción completa

Detalles Bibliográficos
Autores principales: Do, Danh C., Zhang, Yan, Tu, Wei, Hu, Xinyue, Xiao, Xiaojun, Chen, Jingsi, Hao, Haiping, Liu, Zhigang, Li, Jing, Huang, Shau-Ku, Wan, Mei, Gao, Peisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410088/
https://www.ncbi.nlm.nih.gov/pubmed/34101619
http://dx.doi.org/10.1172/jci.insight.148147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410088/
https://www.ncbi.nlm.nih.gov/pubmed/34101619
http://dx.doi.org/10.1172/jci.insight.148147

Ejemplares similares