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STAT4 is expressed in neutrophils and promotes antimicrobial immunity

Signal transducer and activator of transcription 4 (STAT4) is expressed in hematopoietic cells and plays a key role in the differentiation of T helper 1 cells. Although STAT4 is required for immunity to intracellular pathogens, the T cell–independent protective mechanisms of STAT4 are not clearly de...

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Detalles Bibliográficos
Autores principales: Mehrpouya-Bahrami, Pegah, Moriarty, Alina K., De Melo, Paulo, Keeter, W. Coles, Alakhras, Nada S., Nelson, Andrew S., Hoover, Madeline, Barrios, Maria S., Nadler, Jerry L., Serezani, C. Henrique, Kaplan, Mark H., Galkina, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410094/
https://www.ncbi.nlm.nih.gov/pubmed/34138758
http://dx.doi.org/10.1172/jci.insight.141326