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Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice

Fetal growth restriction, or low birth weight, is a strong determinant for eventual obesity and type 2 diabetes. Clinical studies suggest placental mechanistic target of rapamycin (mTOR) signaling regulates fetal birth weight and the metabolic health trajectory of the offspring. In the current study...

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Detalles Bibliográficos
Autores principales: Akhaphong, Brian, Baumann, Daniel C., Beetch, Megan, Lockridge, Amber D., Jo, Seokwon, Wong, Alicia, Zemanovic, Tate, Mohan, Ramkumar, Fondevilla, Danica L., Sia, Michelle, Pineda-Cortel, Maria Ruth B., Alejandro, Emilyn U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410096/
https://www.ncbi.nlm.nih.gov/pubmed/34032632
http://dx.doi.org/10.1172/jci.insight.149271